Pay in installments of $25.00 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Aug 4 - Aug 9
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
LY6E/SCA-2 Recombinant Rabbit mAb (S-2681-56)Product Specification Host Rabbit Antigen LY6E SCA 2 Synonyms Lymphocyte antigen 6E; Ly 6E; Retinoic acid induced gene E protein (RIG E); Stem cell antigen 2 (SCA 2); Thymic shared antigen 1 (TSA 1); 9804; RIGE; SCA2; TSA1 Immunogen Recombinant Protein Location Cell membrane Accession Q16553 Clone Number S 2681 56 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, ICC Reactivity Hu Positive Sample T 47D, HT 29, HCT 116, SW480, SW620, HEK
Product Specification
| Host | Rabbit |
| Antigen | LY6E/SCA-2 |
| Synonyms | Lymphocyte antigen 6E; Ly-6E; Retinoic acid-induced gene E protein (RIG-E); Stem cell antigen 2 (SCA-2); Thymic shared antigen 1 (TSA-1); 9804; RIGE; SCA2; TSA1 |
| Immunogen | Recombinant Protein |
| Location | Cell membrane |
| Accession | Q16553 |
| Clone Number | S-2681-56 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, ICC |
| Reactivity | Hu |
| Positive Sample | T-47D, HT-29, HCT 116, SW480, SW620, HEK-293 |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu |
| IHC-P | 1:250 | Hu |
| ICC | 1:500 | Hu |
Background
LY6E/SCA-2 is a ~14 kDa glycosylphosphatidylinositol-anchored cell-surface protein of the Ly6/uPAR superfamily that is constitutively expressed in thymus, spleen, placenta and many epithelia and is strongly up-regulated by type I interferons; it functions as a context-dependent modulator of immunity and oncogenesis by tuning T-cell receptor/CD3ζ phosphorylation, enhancing HIV-1 and other viral replication while conversely restricting coronavirus entry via spike-protein interference, and its over-expression in multiple tumors promotes immune escape, metastasis and chemoresistance, making it a candidate prognostic marker and therapeutic target.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy